miRNA description for miR-125b-5p |
miRNA accession |
miR-125b-5p |
Species |
Homo sapiens |
miR-125b-5p identified in exosomes derived from the following tissue/cell type |
Colorectal cancer cells [Exosomes]
|
29472616
|
Colorectal cancer cells [Exosomes]
|
29472616
|
Colorectal cancer cells [Exosomes]
|
29472616
|
Lung cells [Microvesicles]
|
20079801
|
Mesenchymal stem cells [Exosomes]
|
33479185
|
Mesenchymal stem cells [Extracellular vesicles]
|
34596354
|
Posterior longitudinal ligament [Small extracellular vesicles]
|
35513391
|
Pulmonary artery endothelial cells [Exosomes]
|
32132543
|
Pulmonary artery endothelial cells [Exosomes]
|
32132543
|
Serum [Exosomes]
|
27883272
|
Serum [Exosomes]
|
27883272
|
Urine [Exosomes]
|
24352158
|
Experiment description of studies that identified miR-125b-5p in exosomes |
1
|
Experiment ID | 1435 |
Identified molecule | miRNA
|
Identification method | miR-chip array
|
PubMed ID |
29472616
|
Organism | Homo sapiens |
Experiment description | Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 |
Authors | Cooks T, Pateras IS, Jenkins LM, Patel KM, Robles AI, Morris J, Forshew T, Appella E, Gorgoulis VG, Harris CC. |
Journal name |
Nat Commun
|
Publication year | 2018 |
Sample | Colorectal cancer cells |
Sample name | HCT116 |
Molecules identified in the study | Protein miRNA |
Methods used in the study | Western blotting miR-chip array |
EV-TRACK |
-
|
|
|
2
|
Experiment ID | 1436 |
Identified molecule | miRNA
|
Identification method | miR-chip array
|
PubMed ID |
29472616
|
Organism | Homo sapiens |
Experiment description | Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 |
Authors | Cooks T, Pateras IS, Jenkins LM, Patel KM, Robles AI, Morris J, Forshew T, Appella E, Gorgoulis VG, Harris CC. |
Journal name |
Nat Commun
|
Publication year | 2018 |
Sample | Colorectal cancer cells |
Sample name | HCT116 |
Molecules identified in the study | Protein miRNA |
Methods used in the study | Western blotting miR-chip array |
EV-TRACK |
-
|
|
|
3
|
Experiment ID | 1437 |
Identified molecule | miRNA
|
Identification method | miR-chip array
|
PubMed ID |
29472616
|
Organism | Homo sapiens |
Experiment description | Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 |
Authors | Cooks T, Pateras IS, Jenkins LM, Patel KM, Robles AI, Morris J, Forshew T, Appella E, Gorgoulis VG, Harris CC. |
Journal name |
Nat Commun
|
Publication year | 2018 |
Sample | Colorectal cancer cells |
Sample name | HCT116 |
Molecules identified in the study | Protein miRNA |
Methods used in the study | Western blotting miR-chip array |
EV-TRACK |
-
|
|
|
4
|
Experiment ID | 324 |
Identified molecule | miRNA
|
Identification method | Microarray or RT-PCR
|
PubMed ID |
20079801
|
Organism | Mus musculus |
Experiment description | Microvesicle entry into marrow cells mediates tissue-specific changes in mRNA by direct delivery of mRNA and induction of transcription |
Authors | Aliotta JM, Pereira M, Johnson KW, de Paz N, Dooner MS, Puente N, Ayala C, Brilliant K, Berz D, Lee D, Ramratnam B, McMillan PN, Hixson DC, Josic D, Quesenberry PJ |
Journal name |
Exp Hematol
|
Publication year | 2010 |
Sample | Lung cells |
Sample name | Lung cells |
Molecules identified in the study | Protein miRNA |
Methods used in the study | FACS RT-PCR |
EV-TRACK |
EV100071: EV-METRIC:14%
|
|
|
5
|
Experiment ID | 1526 |
Identified molecule | miRNA
|
Identification method | Microarray
|
PubMed ID |
33479185
|
Organism | Homo sapiens |
Experiment description | Human umbilical cord mesenchymal stem cell-derived exosomal miR-146a-5p reduces microglial-mediated neuroinflammation via suppression of the IRAK1/TRAF6 signaling pathway after ischemic stroke |
Authors | Zhang Z, Zou X, Zhang R, Xie Y, Feng Z, Li F, Han J, Sun H, Ouyang Q, Hua S, Lv B, Hua T, Liu Z, Cai Y, Zou Y, Tang Y, Jiang X. |
Journal name |
Aging
|
Publication year | 2021 |
Sample | Mesenchymal stem cells |
Sample name | hUMSCs |
Molecules identified in the study | Protein miRNA |
Methods used in the study | Western blotting Microarray |
EV-TRACK |
-
|
|
|
6
|
Experiment ID | 3202 |
Identified molecule | miRNA
|
Identification method | Small RNA sequencing
|
PubMed ID |
34596354
|
Organism | Homo sapiens |
Experiment description | Extracellular vesicles from adipose tissue-derived stem cells alleviate osteoporosis through osteoprotegerin and miR-21-5p |
Authors | Lee KS, Lee J, Kim HK, Yeom SH, Woo CH, Jung YJ, Yun YE, Park SY, Han J, Kim E, Sul JH, Jung JM, Park JH, Choi JS, Cho YW, Jo DG. |
Journal name |
J Extracell Vesicles
|
Publication year | 2021 |
Sample | Mesenchymal stem cells |
Sample name | Adipose tissue-derived stem cells |
Molecules identified in the study | Protein miRNA |
Methods used in the study | Flow cytometry Small RNA sequencing ddPCR |
EV-TRACK |
-
|
|
|
7
|
Experiment ID | 2740 |
Identified molecule | miRNA
|
Identification method | RNA sequencing
|
PubMed ID |
35513391
|
Organism | Homo sapiens |
Experiment description | Small extracellular vesicle-mediated miR-320e transmission promotes osteogenesis in OPLL by targeting TAK1 |
Authors | Xu C, Zhang Z, Liu N, Li L, Zhong H, Wang R, Shi Q, Zhang Z, Wei L, Hu B, Zhang H, Shen X, Wang Y, Liu Y, Yuan W. |
Journal name |
Nat Commun
|
Publication year | 2022 |
Sample | Posterior longitudinal ligament |
Sample name | Posterior longitudinal ligament cells |
Molecules identified in the study | miRNA |
Methods used in the study | RNA sequencing qRT-PCR |
EV-TRACK |
-
|
|
|
8
|
Experiment ID | 1468 |
Identified molecule | miRNA
|
Identification method | RT-PCR
|
PubMed ID |
32132543
|
Organism | Homo sapiens |
Experiment description | Therapeutic potential of KLF2-induced exosomal microRNAs in pulmonary hypertension |
Authors | Sindi HA, Russomanno G, Satta S, Abdul-Salam VB, Jo KB, Qazi-Chaudhry B, Ainscough AJ, Szulcek R, Jan Bogaard H, Morgan CC, Pullamsetti SS, Alzaydi MM, Rhodes CJ, Piva R, Eichstaedt CA, Grünig E, Wilkins MR, Wojciak-Stothard B. |
Journal name |
Nat Commun
|
Publication year | 2020 |
Sample | Pulmonary artery endothelial cells |
Sample name | HPAEC |
Molecules identified in the study | miRNA |
Methods used in the study | RT-PCR |
EV-TRACK |
-
|
|
|
9
|
Experiment ID | 1469 |
Identified molecule | miRNA
|
Identification method | RT-PCR
|
PubMed ID |
32132543
|
Organism | Homo sapiens |
Experiment description | Therapeutic potential of KLF2-induced exosomal microRNAs in pulmonary hypertension |
Authors | Sindi HA, Russomanno G, Satta S, Abdul-Salam VB, Jo KB, Qazi-Chaudhry B, Ainscough AJ, Szulcek R, Jan Bogaard H, Morgan CC, Pullamsetti SS, Alzaydi MM, Rhodes CJ, Piva R, Eichstaedt CA, Grünig E, Wilkins MR, Wojciak-Stothard B. |
Journal name |
Nat Commun
|
Publication year | 2020 |
Sample | Pulmonary artery endothelial cells |
Sample name | HPAEC |
Molecules identified in the study | miRNA |
Methods used in the study | RT-PCR |
EV-TRACK |
-
|
|
|
10
|
Experiment ID | 1198 |
Identified molecule | miRNA
|
Identification method | Microarray
|
PubMed ID |
27883272
|
Organism | Homo sapiens |
Experiment description | Circulating adipocyte-derived exosomal MicroRNAs associated with decreased insulin resistance after gastric bypass. |
Authors | Hubal MJ, Nadler EP, Ferrante SC, Barberio MD, Suh JH, Wang J, Dohm GL, Pories WJ, Mietus-Snyder M, Freishtat RJ. |
Journal name |
Obesity (Silver Spring).
|
Publication year | 2017 |
Sample | Serum |
Sample name | Two weeks before bariatric surgery |
Molecules identified in the study | miRNA Metabolites |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
11
|
Experiment ID | 1199 |
Identified molecule | miRNA
|
Identification method | Microarray
|
PubMed ID |
27883272
|
Organism | Homo sapiens |
Experiment description | Circulating adipocyte-derived exosomal MicroRNAs associated with decreased insulin resistance after gastric bypass. |
Authors | Hubal MJ, Nadler EP, Ferrante SC, Barberio MD, Suh JH, Wang J, Dohm GL, Pories WJ, Mietus-Snyder M, Freishtat RJ. |
Journal name |
Obesity (Silver Spring).
|
Publication year | 2017 |
Sample | Serum |
Sample name | One year after bariatric surgery |
Molecules identified in the study | miRNA Metabolites |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
12
|
Experiment ID | 357 |
Identified molecule | miRNA
|
Identification method | RNA deep sequencing
|
PubMed ID |
24352158
|
Organism | Homo sapiens |
Experiment description | Characterization and deep sequencing analysis of exosomal miRNA in human urine |
Authors | Lesley Cheng, Xin Sun, Bradley M. Coleman, Andrew F. Hill |
Journal name |
Kidney Int
|
Publication year | 2014 |
Sample | Urine |
Sample name | Urine - Normal |
Molecules identified in the study | miRNA |
Methods used in the study | RNA deep sequencing |
EV-TRACK |
EV140147: EV-METRIC:44%, 0%, 22%
|
|
|